Lamotrigine ODT-Induced Seizure in a 3-Year-Old Child after Accidental Ingestion

Ashley Griswold; Briana Tully; Kenneth Katz; Gillian Beauchamp; Matthew Cook; Robert Cannon

doi:10.1155/2019/2675931

Case Reports in Emergency Medicine (Jan 2019)

Lamotrigine ODT-Induced Seizure in a 3-Year-Old Child after Accidental Ingestion

Ashley Griswold,
Briana Tully,
Kenneth Katz,
Gillian Beauchamp,
Matthew Cook,
Robert Cannon

Affiliations

Ashley Griswold: Department of Pediatrics, Lehigh Valley Health Network/University of South Florida Morsani College of Medicine, Cedar Crest Boulevard & I-78, Allentown, PA 18103, USA
Briana Tully: Department of Emergency and Hospital Medicine, Lehigh Valley Health Network/University of South Florida Morsani College of Medicine, Cedar Crest Boulevard & I-78, Allentown, PA 18103, USA
Kenneth Katz: Department of Emergency and Hospital Medicine, Lehigh Valley Health Network/University of South Florida Morsani College of Medicine, Cedar Crest Boulevard & I-78, Allentown, PA 18103, USA
Gillian Beauchamp: Department of Emergency and Hospital Medicine, Lehigh Valley Health Network/University of South Florida Morsani College of Medicine, Cedar Crest Boulevard & I-78, Allentown, PA 18103, USA
Matthew Cook: Department of Emergency and Hospital Medicine, Lehigh Valley Health Network/University of South Florida Morsani College of Medicine, Cedar Crest Boulevard & I-78, Allentown, PA 18103, USA
Robert Cannon: Department of Emergency and Hospital Medicine, Lehigh Valley Health Network/University of South Florida Morsani College of Medicine, Cedar Crest Boulevard & I-78, Allentown, PA 18103, USA

DOI: https://doi.org/10.1155/2019/2675931
Journal volume & issue: Vol. 2019

Abstract

Read online

Lamotrigine is a new generation antiepileptic which blocks sodium channels and can cause significant toxicity in overdose. A case of a three-year-old child who suffered a seizure and required endotracheal intubation after accidental lamotrigine ingestion is presented. The lamotrigine concentration measured 23.2 mcg/mL which is the highest reported after accidental pediatric exposure. A review of the literature regarding pediatric lamotrigine poisoning is also included.

Published in Case Reports in Emergency Medicine

ISSN: 2090-648X (Print); 2090-6498 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Medical emergencies. Critical care. Intensive care. First aid
Website: https://onlinelibrary.wiley.com/journal/6058

About the journal