Clinical Dermatology Review (Oct 2024)
Subcutaneous Panniculitis-like T-cell Lymphoma
Abstract
Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a primary, rare cutaneous T-cell lymphoma that resembles panniculitis and accounts for <1% of all peripheral T-cell lymphomas. It is characterized by multiple subcutaneous nodules and plaques, which usually involve the extremities. Histopathological findings include the presence of neoplastic T-cell surround and disrupt individual adipocyte membranes. Immunohistochemistry will confirm diagnosis by CD8+ and CD56− cells. Here, we report a case of a 29-year-old female who presented with cutaneous panniculitis-like lesions diagnosed with cutaneous T-cell lymphoma with the help of histopathology and immunohistochemistry.
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