Annals of Human Biology (Nov 2017)

An anthropometric survey of US pre-term and full-term neonates

  • Susan M. Abdel-Rahman,
  • Ian M. Paul,
  • Paula Delmore,
  • Laura James,
  • Laura Fearn,
  • Andrew M. Atz,
  • Brenda B. Poindexter,
  • Amira Al-Uzri,
  • Andrew Lewandowski,
  • Barrie L. Harper,
  • P. Brian Smith,
  • for the Best Pharmaceuticals for Children Act – Pediatric Trials Network

DOI
https://doi.org/10.1080/03014460.2017.1392603
Journal volume & issue
Vol. 44, no. 8
pp. 678 – 686

Abstract

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Background: Anthropometric data prove valuable for screening and monitoring various medical conditions. In young infants, however, only weight, length and head circumference are represented in publicly accessible databases. Aim: To characterise length and circumferential measures in pre-term and full-term infants up to 90 days post-natal. Subjects and methods: In eight US medical centres, trained raters recorded humeral, ulnar, femoral, tibial and fibular lengths along with mid-upper arm, mid-thigh, chest, abdominal and neck circumference. Data were pooled by post-menstrual age into 1-week intervals and population curves created using the lambda, mu and sigma (LMS) method. Goodness-of-fit was assessed by examining de-trended quantile-quantile plots, Q statistics and fitted centiles overlaid on empirical centiles. Results: In total, 2097 infants were enrolled in this study with a mean ± SD gestational age and post-natal age of 37.1 ± 3.3 weeks and 27.3 ± 25.3 days, respectively. A re-scale option was used to describe all curves. The resultant models reliably characterised anthropometric measures from 33–52 weeks PMA, with less certainty at the extremes (27–55 weeks). Conclusion: The population curves generated under this investigation expand existing reference data on a comprehensive set of anthropometric traits in infants through the first 90 days post-natal.

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