Acta Crystallographica Section E: Crystallographic Communications (Jun 2020)

Febuxostat ethanol monosolvate

  • Thomas Gelbrich,
  • Volker Kahlenberg,
  • Verena Adamer,
  • Sven Nerdinger,
  • Ulrich J. Griesser

DOI
https://doi.org/10.1107/S2056989020006076
Journal volume & issue
Vol. 76, no. 6
pp. 816 – 819

Abstract

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The title compound, 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic acid ethanol monosolvate, C16H16N2O3S·C2H6O, (I), displays intermolecular O—H...O and O—H...N bonds in which the carboxyl group of the febuxostat molecule and the hydroxyl group of the ethanol molecule serve as hydrogen-bond donor sites. These interactions result in a helical hydrogen-bonded chain structure. The title structure is isostructural with a previously reported methanol analogue.

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