Duloxetine‐induced syndrome of inappropriate antidiuretic hormone secretion in a patient with neuropathic pain

Nobuyuki Takahashi; Yukiko Mori; Kenji Momo; Hidetomo Murakami; Hironori Tanaka

doi:10.1002/ccr3.9526

Clinical Case Reports (Nov 2024)

Duloxetine‐induced syndrome of inappropriate antidiuretic hormone secretion in a patient with neuropathic pain

Nobuyuki Takahashi,
Yukiko Mori,
Kenji Momo,
Hidetomo Murakami,
Hironori Tanaka

Affiliations

Nobuyuki Takahashi: Department of Pharmacy Showa University East Hospital Shinagawa‐ku Tokyo Japan
Yukiko Mori: Department of Neurology Showa University School of Medicine Shinagawa‐ku Tokyo Japan
Kenji Momo: Department of Hospital Pharmaceutics, School of Pharmacy Showa University Shinagawa‐ku Tokyo Japan
Hidetomo Murakami: Department of Neurology Showa University School of Medicine Shinagawa‐ku Tokyo Japan
Hironori Tanaka: Department of Pharmacy Showa University East Hospital Shinagawa‐ku Tokyo Japan

DOI: https://doi.org/10.1002/ccr3.9526
Journal volume & issue: Vol. 12, no. 11
pp. n/a – n/a

Abstract

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Key Clinical Message Syndrome of inappropriate antidiuretic hormone secretion (SIADH) induces hyponatremia accompanied by uric acid reduction. We report a case of a patient with small‐cell lung cancer who developed SIADH with hypouricemia after duloxetine treatment and discuss the potential underlying mechanisms. SIADH and hypouricemia improved after duloxetine was switched to mirogabalin.

Published in Clinical Case Reports

ISSN: 2050-0904 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Medicine (General)
Website: https://onlinelibrary.wiley.com/journal/20500904

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