Chronic Nephropathy 5 degree multicomplicated, secondary to primary hyperoxaluria. Value of the etiologic diagnosis

Abstract

A young patient of African origin is presented, with previous history of urinary calcull observed at the age of 10 years and recurrent urinary tract infections and severe acute pyelonephritis; seven years later he arrived at stage 5 of the chronic kidney disease without nephrology monitoring. He started therapy with automated peritoneal dialysis and then hemodialysis. He received renal transplant of alive related donor that failed the tenth day in the context mediated by antibody rejection and evidence of crystals of calcium oxalate in the renal parenchyma and urinary spaces that confirmed the diagnosis of primary hyperoxaluria. Returned to periodical hemodialysis, he is exposed to a liver graft donated by another sister, with adequate recovery. He was admitted at four months for sepsis, giant abscess of the anterior abdominal wall, cerebral infarction, shock and death. It is important to establish the etiological diagnosis of the underlying nephropathy to decide the appropriate treatment of therapy.

Keywords

• fallo renal crónico
• hiperoxaluria primaria