Pharmaceutical standardization of Agastyaharitaki Avaleha

Abstract

Background: Agastyaharitaki Avaleha(AHA) is an important ayurvedic polyherbal formulation, mentioned in the Ayurvedic Formulary of India (AFI, Part III). It is routinely prescribed in Pratishyaya(chronic rhinitis), kasa(cough), and shwasa(asthma) by ayurvedic physicians. Aim: The objective was to develop the standard manufacturing procedure (SMP) and quality standards of AHA. Materials and methods: In the current research work, AHA was prepared in three batches as per standard guidelines mentioned in AFI. The drug was prepared in three batches to generate SMP. Results: Average percentage yield of Prakshepa(Pippali) was 88.67%; during the procedure of Avaleha, the temperature was maintained in between 90°C and 100°C and observed Darvi Pralepatvam at 93°C, Tantumatvam at 94°C, Apsumajjanam at 94°C, and sthiratvam at 95°C. Average yield was found as 9570 g. It took 20.10 h to complete the preparation of avaleha. Conclusion: The current study reflects standardization and opens a new concept to standardize the product.

Keywords

• agastyaharitaki avaleha
• pharmaceutical
• standarization