Functional Connectivity as an Index of Brain Changes Following a Unicycle Intervention: A Graph-Theoretical Network Analysis

Abstract

Grey matter volume reductions in the right superior temporal gyrus (rSTG) were observed in young adults who learned to ride a unicycle. As these decreases were correlated with the acquired ability in unicycling, the authors interpreted the change as a brain tissue reorganization to increase postural control’s automated and efficient coordination. The current study aims to further corroborate this interpretation by looking at changes in the functional brain network in the very same sample of participants. For this reason, we applied graph theory, a mathematics field used to study network structure functionality. Four global and two local graph-theoretical parameters were calculated to measure whole brain and rSTG specific changes in functional network activity following the three-week-unicycle training. Findings revealed that the Local Efficiency of the rSTG was significantly elevated after the intervention indicating an increase in fault tolerance of the rSTG, possibly reflecting decentralisation of rSTG specific functions to neighbouring nodes. Thus, the increased Local Efficiency may indicate increased task efficiency by decentralising the processing of functions crucial for balance.

Keywords

• graph theory
• balance intervention
• unicycle
• functional brain network
• fMRI