Post-operative radiotherapy in the management of metastatic inflammatory breast cancer

Abstract

With this review, we aimed to describe the role of adjuvant radiotherapy in the therapeutic management of metastatic inflammatory breast cancer, a rare and aggressive disease historically characterized by high rates of recurrence and poor prognosis. In the context of a multimodality approach, Post-Mastectomy Radiotherapy (PMRT) affirms its role as an appriopriate treatment strategy to improve loco-regional tumor control in selected patients. Further validation in prospective trials is required to better define a standardized therapeutic management of this disease.