Optical molecular imaging can differentiate metastatic from benign lymph nodes in head and neck cancer

Naoki Nishio; Nynke S. van den Berg; Stan van Keulen; Brock A. Martin; Shayan Fakurnejad; Nutte Teraphongphom; Stefania U. Chirita; Nicholas J. Oberhelman; Guolan Lu; Crista E. Horton; Michael J. Kaplan; Vasu Divi; A. Dimitrios Colevas; Eben L. Rosenthal

doi:10.1038/s41467-019-13076-7

Nature Communications (Nov 2019)

Optical molecular imaging can differentiate metastatic from benign lymph nodes in head and neck cancer

Naoki Nishio,
Nynke S. van den Berg,
Stan van Keulen,
Brock A. Martin,
Shayan Fakurnejad,
Nutte Teraphongphom,
Stefania U. Chirita,
Nicholas J. Oberhelman,
Guolan Lu,
Crista E. Horton,
Michael J. Kaplan,
Vasu Divi,
A. Dimitrios Colevas,
Eben L. Rosenthal

Affiliations

Naoki Nishio: Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine
Nynke S. van den Berg: Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine
Stan van Keulen: Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine
Brock A. Martin: Department of Pathology, Stanford University School of Medicine
Shayan Fakurnejad: Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine
Nutte Teraphongphom: Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine
Stefania U. Chirita: Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine
Nicholas J. Oberhelman: Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine
Guolan Lu: Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine
Crista E. Horton: Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine
Michael J. Kaplan: Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine
Vasu Divi: Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine
A. Dimitrios Colevas: Department of Medicine, Division of Medical Oncology, Stanford University School of Medicine
Eben L. Rosenthal: Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine

DOI: https://doi.org/10.1038/s41467-019-13076-7
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 10

Abstract

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Imaging metastatic disease burden in lymph nodes is important for surgical decision making. Here, the authors use an antibody-dye conjugate to distinguish between metastatic and benign lymph nodes in head and neck cancer.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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