Phenotype-based drug screening reveals association between venetoclax response and differentiation stage in acute myeloid leukemia

• Heikki Kuusanmäki,
• Aino-Maija Leppä,
• Petri Pölönen,
• Mika Kontro,
• Olli Dufva,
• Debashish Deb,
• Bhagwan Yadav,
• Oscar Brück,
• Ashwini Kumar,
• Hele Everaus,
• Bjørn T. Gjertsen,
• Merja Heinäniemi,
• Kimmo Porkka,
• Satu Mustjoki,
• Caroline A. Heckman

Affiliations

Heikki Kuusanmäki

Institute for Molecular Medicine Finland, Helsinki Institute of Life Science, University of Helsinki, Helsinki;Hematology Research Unit, Helsinki University Hospital Comprehensive Cancer Center, Helsinki

Aino-Maija Leppä

Institute for Molecular Medicine Finland, Helsinki Institute of Life Science, University of Helsinki, Helsinki

Petri Pölönen

Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio, Finland

Mika Kontro

Hematology Research Unit, Helsinki University Hospital Comprehensive Cancer Center, Helsinki

Olli Dufva

Hematology Research Unit, Helsinki University Hospital Comprehensive Cancer Center, Helsinki

Debashish Deb

Institute for Molecular Medicine Finland, Helsinki Institute of Life Science, University of Helsinki, Helsinki

Bhagwan Yadav

Hematology Research Unit, Helsinki University Hospital Comprehensive Cancer Center, Helsinki

Oscar Brück

Hematology Research Unit, Helsinki University Hospital Comprehensive Cancer Center, Helsinki

Ashwini Kumar

Institute for Molecular Medicine Finland, Helsinki Institute of Life Science, University of Helsinki, Helsinki

Hele Everaus

Department of Hematology and Oncology, University of Tartu, Tartu, Estonia

Bjørn T. Gjertsen

Centre for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Bergen, Norway

Merja Heinäniemi

Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio, Finland

Kimmo Porkka

Hematology Research Unit, Helsinki University Hospital Comprehensive Cancer Center, Helsinki

Satu Mustjoki

Hematology Research Unit, Helsinki University Hospital Comprehensive Cancer Center, Helsinki;Translational Immunology Research Program and Department of Clinical Chemistry and Hematology, University of Helsinki, Helsinki, Finland

Caroline A. Heckman

Institute for Molecular Medicine Finland, Helsinki Institute of Life Science, University of Helsinki, Helsinki