Nature Communications (Feb 2021)
Addressable nanoantennas with cleared hotspots for single-molecule detection on a portable smartphone microscope
- Kateryna Trofymchuk,
- Viktorija Glembockyte,
- Lennart Grabenhorst,
- Florian Steiner,
- Carolin Vietz,
- Cindy Close,
- Martina Pfeiffer,
- Lars Richter,
- Max L. Schütte,
- Florian Selbach,
- Renukka Yaadav,
- Jonas Zähringer,
- Qingshan Wei,
- Aydogan Ozcan,
- Birka Lalkens,
- Guillermo P. Acuna,
- Philip Tinnefeld
Affiliations
- Kateryna Trofymchuk
- Department of Chemistry and Center for NanoScience, Ludwig-Maximilians-Universität München
- Viktorija Glembockyte
- Department of Chemistry and Center for NanoScience, Ludwig-Maximilians-Universität München
- Lennart Grabenhorst
- Department of Chemistry and Center for NanoScience, Ludwig-Maximilians-Universität München
- Florian Steiner
- Department of Chemistry and Center for NanoScience, Ludwig-Maximilians-Universität München
- Carolin Vietz
- Institute for Physical and Theoretical Chemistry - NanoBioScience and Braunschweig Integrated Centre of Systems Biology (BRICS), Technische Universität Braunschweig
- Cindy Close
- Department of Chemistry and Center for NanoScience, Ludwig-Maximilians-Universität München
- Martina Pfeiffer
- Department of Chemistry and Center for NanoScience, Ludwig-Maximilians-Universität München
- Lars Richter
- Institute for Physical and Theoretical Chemistry - NanoBioScience and Braunschweig Integrated Centre of Systems Biology (BRICS), Technische Universität Braunschweig
- Max L. Schütte
- Institute for Physical and Theoretical Chemistry - NanoBioScience and Braunschweig Integrated Centre of Systems Biology (BRICS), Technische Universität Braunschweig
- Florian Selbach
- Department of Chemistry and Center for NanoScience, Ludwig-Maximilians-Universität München
- Renukka Yaadav
- Department of Chemistry and Center for NanoScience, Ludwig-Maximilians-Universität München
- Jonas Zähringer
- Department of Chemistry and Center for NanoScience, Ludwig-Maximilians-Universität München
- Qingshan Wei
- Department of Chemical and Biomolecular Engineering, North Carolina State University
- Aydogan Ozcan
- Electrical & Computer Engineering Department, Bioengineering Department, California NanoSystems Institute (CNSI), and Department of Surgery, University of California
- Birka Lalkens
- Institut für Halbleitertechnik, Laboratory for Emerging Nanometrology LENA
- Guillermo P. Acuna
- Département de Physique - Photonic Nanosystems, Université de Fribourg - Faculté des Sciences et Médicine
- Philip Tinnefeld
- Department of Chemistry and Center for NanoScience, Ludwig-Maximilians-Universität München
- DOI
- https://doi.org/10.1038/s41467-021-21238-9
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 8
Abstract
Single-molecule fluorescence currently requires specialized imaging equipment due to the low signal of a single emitter. Here the authors introduce NanoAntennas with Cleared HOtSpots (NACHOS) to boost the signal sufficient for detection of a single emitter by a smartphone, opening the door to point-of-care applications.
