Cefiderocol treatment of Pseudomonas aeruginosa and extensively drug-resistant Acinetobacter baumannii retained spinal hardware infection causing reversible acute interstitial nephritis

Abstract

Infections with extensively drug-resistant Acinetobacter baumannii (XDRAB) have limited therapeutic options. We report successful salvage treatment of XDRAB and Pseudomonas aeruginosa-infected retained spinal hardware with cefiderocol, despite the development of reversible acute interstitial nephritis after 32 days of treatment.

Keywords

• Extensively drug-resistant Acinetobacter baumannii (XDRAB)
• Cefiderocol
• MDR Gram-negative
• Spinal hardware infection
• Biofilm
• Acute interstitial nephritis