Nature Communications (Dec 2016)
A large-scale genome-wide association and meta-analysis identified four novel susceptibility loci for leprosy
- Zhenzhen Wang,
- Yonghu Sun,
- Xi’an Fu,
- Gongqi Yu,
- Chuan Wang,
- Fangfang Bao,
- Zhenhua Yue,
- Jianke Li,
- Lele Sun,
- Astrid Irwanto,
- Yongxiang Yu,
- Mingfei Chen,
- Zihao Mi,
- Honglei Wang,
- Pengcheng Huai,
- Yi Li,
- Tiantian Du,
- Wenjun Yu,
- Yang Xia,
- Hailu Xiao,
- Jiabao You,
- Jinghui Li,
- Qing Yang,
- Na Wang,
- Panpan Shang,
- Guiye Niu,
- Xiaojun Chi,
- Xiuhuan Wang,
- Jing Cao,
- Xiujun Cheng,
- Hong Liu,
- Jianjun Liu,
- Furen Zhang
Affiliations
- Zhenzhen Wang
- Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences
- Yonghu Sun
- Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences
- Xi’an Fu
- Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences
- Gongqi Yu
- Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences
- Chuan Wang
- Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences
- Fangfang Bao
- Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences
- Zhenhua Yue
- Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences
- Jianke Li
- Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences
- Lele Sun
- Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences
- Astrid Irwanto
- Human Genetics, Genome Institute of Singapore
- Yongxiang Yu
- Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences
- Mingfei Chen
- Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences
- Zihao Mi
- Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences
- Honglei Wang
- Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences
- Pengcheng Huai
- Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences
- Yi Li
- Human Genetics, Genome Institute of Singapore
- Tiantian Du
- Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences
- Wenjun Yu
- Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences
- Yang Xia
- Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences
- Hailu Xiao
- Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences
- Jiabao You
- Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences
- Jinghui Li
- Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences
- Qing Yang
- Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences
- Na Wang
- Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences
- Panpan Shang
- Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences
- Guiye Niu
- Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences
- Xiaojun Chi
- Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences
- Xiuhuan Wang
- Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences
- Jing Cao
- Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences
- Xiujun Cheng
- Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences
- Hong Liu
- Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences
- Jianjun Liu
- Human Genetics, Genome Institute of Singapore
- Furen Zhang
- Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences
- DOI
- https://doi.org/10.1038/ncomms13760
- Journal volume & issue
-
Vol. 7,
no. 1
pp. 1 – 8
Abstract
Previous studies have shown genetic associations between leprosy and 18 different genes/loci. Here, Wang and colleagues perform genome-wide association study in Han Chinese leprosy patients and describe four novel loci to be associated to the disease.