A Prospective comparative study of Incidence of early Suture site infection following incisional negative pressure wound therapy and Povidone-iodine dressing in a post-operative emergency non-traumatic exploratory laparotomy

Abstract

Aims and Objectives: The study aimed to assess the efficacy of incisional negative pressure wound therapy (iNPWT) in reducing the risk of suture site infections (SSI) in patients undergoing post-operative emergency non-traumatic laparotomy. Materials and Methods: A cross-sectional observational prospective study was conducted in a tertiary care setup in a rural area between March 2018 and July 2018. Fifty emergency exploratory laparoto-mies performed for non-traumatic reasons were included. Patients were randomized into two groups: one receiving conventional povidone-iodine dressing and the other receiving iNPWT over the main wound. After 7 days, SSI was assessed using the center for disease control and prevention's criteria. Results: iNPWT demonstrated a significant reduction in the risk of SSI development when compared to conventional povidone-iodine dressing (p <0.001) within a 95% confidence interval. The odds of SSI development with conventional povidone-iodine dressing were found to be 8.48 times higher com-pared to iNPWT. The 95% confidence interval for the odds ratio was 2.21-32.45. Conclusion: Incisional negative pressure wound therapy is superior to conventional povidone-iodine dressing in preventing the onset of SSI in patients undergoing emergency laparotomy for non-traumatic conditions.

Keywords

• incisional negative pressure wound therapy
• suture site infection
• povidone-iodine dressings