Ожирение и метаболизм (Nov 2015)
The effect of type 2 diabetes and its drug therapy on bone quality.
Abstract
Individuals with type 2 diabetes have increased risk of fragility fractures. It’s not completely clear by which mechanism type 2 diabetes increases skeletal fragility. A combination of factors, including an increased risk of falling (contributed by complications of the disease) and impaired bone quality apparently leads to a greater fracture risk. Some cl asses of drug therapy for type 2 diabetes may also increase fracture risk by their own mechanism of action.
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