Clinical observation of a patient with thrombotic thrombocytopenic purpura with renal and intestinal lesions

Abstract

The article presents a brief description of a rare disease - thrombotic thrombocytopenic purpura (Moshkovits - disease), which is based on the deficiency of ADAMTS-13 metalloproteinase, leading to the development of thrombotic microangiopathy with the defeat of vital organs. The article also describes the clinical observation of a patient with the Moshkovits - disease. The features of the above observation are involvement in the pathological process of the kidneys and intestines, while in the classical descriptions of the disease there is a predominant lesion of the Central nervous system, as well as the genetic form of the disease.

Keywords

• adamts-13
• thrombotic thrombocytopenic purpura
• thrombotic microangiopathy
• moshkovits - disease
• adamts-13