Respiratory Medicine Case Reports (Jan 2024)

Metastatic pulmonary calcification in a renal transplant recipient

  • Tetsuro Maeda,
  • Margaret Connolly,
  • Joseph Modrak,
  • Irene Perillo

Journal volume & issue
Vol. 50
p. 102043

Abstract

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Metastatic pulmonary calcification (MPC) is a metabolic disorder characterized by an ectopic deposition of calcium in the lung parenchyma, prevalent in patients with chronic kidney disease. A combination of parenchymal lung abnormalities on high resolution chest computed tomography (CT) and pulmonary radiotracer uptake in 99mTc-methyl diphosphate (MDP) bone scintigraphy can establish diagnosis of MPC. We herein present a case of MPC with documented stability of chest CT abnormalities after renal transplant. We also describe novel findings of diffuse pulmonary uptake of 18F-sodium fluoride, a calcium-avid radiotracer, in positron emission tomography (PET)/CT performed in the same patient.

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