Gemcitabine Monotherapy Associated with Posterior Reversible Encephalopathy Syndrome

Abstract

Posterior reversible encephalopathy syndrome is a clinicoradiologic entity that may present with headaches, altered mental status, seizures and visual loss as well as specific neuroimaging findings. We report a case of a 74-year-old woman receiving adjuvant gemcitabine chemotherapy as monotherapy for a stage IIa pancreatic adenocarcinoma, who developed posterior reversible encephalopathy syndrome.

Keywords

• Posterior reversible encephalopathy syndrome
• Gemcitabine
• Chemotherapy