An interventional study of baicalin on neuronal pentraxin-1, neuronal pentraxin-2, and C-reactive protein in Alzheimer’s disease rat model

Zhao Jing-Kun; Hou Si-Jia; Zhao Ji-Wei; Yu Hong-Li; Duan Shu-Rong

doi:10.1515/tnsci-2022-0298

Translational Neuroscience (Sep 2023)

An interventional study of baicalin on neuronal pentraxin-1, neuronal pentraxin-2, and C-reactive protein in Alzheimer’s disease rat model

Zhao Jing-Kun,
Hou Si-Jia,
Zhao Ji-Wei,
Yu Hong-Li,
Duan Shu-Rong

Affiliations

Zhao Jing-Kun: Department of Neurology, The First Affiliated Hospital of Harbin Medical University, No. 23 Postal Street, Nangang District, Harbin150001, China
Hou Si-Jia: Department of Neurology, The General Hospital of Heilongjiang Province Land Reclamation Bureau, Harbin150088, China
Zhao Ji-Wei: Department of Neurology, The First Affiliated Hospital of Harbin Medical University, No. 23 Postal Street, Nangang District, Harbin150001, China
Yu Hong-Li: Department of Neurology, The First Affiliated Hospital of Harbin Medical University, No. 23 Postal Street, Nangang District, Harbin150001, China
Duan Shu-Rong: Department of Neurology, The First Affiliated Hospital of Harbin Medical University, No. 23 Postal Street, Nangang District, Harbin150001, China

DOI: https://doi.org/10.1515/tnsci-2022-0298
Journal volume & issue: Vol. 14, no. 1
pp. 1577 – 90

Abstract

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Baicalin has been shown to promote spatial learning and neural regeneration, which might increase the differentiation of neural stem cells in Alzheimer’s disease (AD) rat models. We aimed to study the role of baicalin on neuronal pentraxin-1 (NPTX-1), neuronal pentraxin-2 (NPTX-2), and C-reactive protein (CRP) in AD model rats.

Published in Translational Neuroscience

ISSN: 2081-6936 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry
Website: http://www.degruyter.com/view/j/tnsci

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Abstract

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