Bibliometric and visualized analysis of the correlation between sarcopenia and chronic liver diseases from 2000 to 2023

Abstract

Abstract Aims Chronic liver disease (CLD) is increasingly recognized as a significant global public health threat, with morbidity and mortality rates remaining high. Evidence suggests that sarcopenia independently increases the risk of CLD and negatively impacts various clinical outcomes, including survival, quality of life, and the emergence of additional complications in patients with CLD. This study aimed to give a bibliometric analysis to examine the correlation between sarcopenia and CLD from a literature perspective. Methods To understand the structure of this research field, we employed VOSviewer. The research on the correlation between long‐term liver disease and sarcopenia was obtained from the Web of Science Core Collection. VOSviewer 1.6.19.0 was utilized to examine and illustrate these publications, encompassing yearly patterns in the domain, focal points of research, significant articles, authors, journals, and organizations. Moreover, according to the results of the cluster analysis of keywords, we further searched and classified related studies to discuss. Results This study provides a comprehensive analysis of current research trends, international collaboration models, fundamental understandings, key focus areas, and future research areas in the field of sarcopenia and CLD by reviewing publications from January 1, 2000 to December 31, 2023. Over the past 24 years, research in the field of sarcopenia and CLD has deepened, with a gradual increase in publications and citations from various countries, institutions, and authors. Keyword analysis of sarcopenia and CLD indicates that current research predominantly focuses on several key areas, including obesity, metabolic syndrome, hepatic steatosis, insulin resistance, inflammation, and nutrition therapy. Conclusion This study provided a visual representation of the current research on the correlation between CLD and sarcopenia, including publication trends, global collaboration patterns, and research hotspots. This research contributes significantly by summarizing and discussing current research trends in sarcopenia and CLD, offering valuable insights into the complex relationship, and highlighting research trends, collaborations, and future directions in clinical treatment.

Keywords

• bibliometric
• chronic liver disease
• inflammation
• insulin resistance
• metabolic syndrome
• muscle