mBio (Oct 2021)

Antimicrobial Peptides—or How Our Ancestors Learned to Control the Microbiome

  • Thomas C. G. Bosch,
  • Michael Zasloff

DOI
https://doi.org/10.1128/mBio.01847-21
Journal volume & issue
Vol. 12, no. 5

Abstract

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Antimicrobial peptides (AMPs) are short and generally positively charged peptides found in a wide variety of life forms from microorganisms to humans. Their wide range of activity against pathogens, including Gram-positive and -negative bacteria, yeasts, fungi, and enveloped viruses makes them a fundamental component of innate immunity.