Nature Communications (Jun 2021)

The architecture of the SARS-CoV-2 RNA genome inside virion

  • Changchang Cao,
  • Zhaokui Cai,
  • Xia Xiao,
  • Jian Rao,
  • Juan Chen,
  • Naijing Hu,
  • Minnan Yang,
  • Xiaorui Xing,
  • Yongle Wang,
  • Manman Li,
  • Bing Zhou,
  • Xiangxi Wang,
  • Jianwei Wang,
  • Yuanchao Xue

DOI
https://doi.org/10.1038/s41467-021-22785-x
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 14

Abstract

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Secondary structures and long-range RNA interactions of the SARS-CoV-2 genome have been investigated by various sequencing methods. Here the authors use an RNA-RNA hybrid sequencing method to predict the secondary and tertiary structure of the SRAS-CoV-2 RNA genome in the virion.