GLOBAL LONGITUDINAL STRAIN OF THE LEFT VENTRICLE after coronary stenting in stable ischemic heart d

Abstract

Aim. To evaluate the global longitudinal strain of the left ventricle (LV) after coronary stenting (CS) in patients with stable ischemic heart disease (IHD).Material and methods. Totally, 50 IHD patients included (35 men, 15 women, age 59,3±6,89 y.). All had indications for CS. Syntax Score was not higher than 22 units (11,78±6,77 units). Before and during the first week after CS all patients underwent standard echocardiography (EchoCG), where the Global Longitudinal Strain-GLSLV was assessed with “AFI” option. All patients also got quantitative measurement of troponin I and MB-creatinkinase (CK-MB) before intervention, in 6 hours and in 24 hours after stenting.Results. Before CS, in 21 patient there was normal GLSLV (-18,0% and less), in 29 GLSLV decreased (more than -18%). After stenting the patients with improvement of GLSLV were marked (n=28) and with worsening of GLSLV (n=22). During early postoperation period there were no any clinically significant complications, electrocardiographic changes, worsenings of local contractility. In worsening of GLSLV group there was increase of troponin I and CK MB in 6 hours and in 24 hours after stenting, not more than threshold value of acute coronary syndrome (ACS).Conclusion. Worsening of global longitudinal strain of the LV after CA stenting was found in 44% of stable IHD patients. Negative dynamics of GLSLV was associated with an increase of troponin I, CK-MB levels in 6 and 24 hours after CS not higher significant for ACS level. Worsening of global strain of the LV and increase of troponin, probably, can be explained by embolism of microcirculatory pool during CA stenting. Damage of myocardium during stenting further determines the decrease of the strain in patients with such increase at the baseline.

Keywords

• ischemic heart disease
• global longitudinal strain of the left ventricle
• coronary stenting
• troponin i