Combined CXCR3/CXCR4 measurements are of high prognostic value in chronic lymphocytic leukemia due to negative co-operativity of the receptors

• Sylvia Ganghammer,
• Julia Gutjahr,
• Evelyn Hutterer,
• Peter W. Krenn,
• Susanne Pucher,
• Claudia Zelle-Rieser,
• Karin Jöhrer,
• Maikel Wijtmans,
• Rob Leurs,
• Martine J. Smit,
• Valter Gattei,
• Richard Greil,
• Tanja N. Hartmann

Affiliations

Sylvia Ganghammer

Laboratory for Immunological and Molecular Cancer Research, 3rd Medical Department with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncologic Center, Paracelsus Medical University, Salzburg, Austria;Salzburg Cancer Research Institute, Austria

Julia Gutjahr

Laboratory for Immunological and Molecular Cancer Research, 3rd Medical Department with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncologic Center, Paracelsus Medical University, Salzburg, Austria;Salzburg Cancer Research Institute, Austria

Evelyn Hutterer

Laboratory for Immunological and Molecular Cancer Research, 3rd Medical Department with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncologic Center, Paracelsus Medical University, Salzburg, Austria;Salzburg Cancer Research Institute, Austria

Peter W. Krenn

Laboratory for Immunological and Molecular Cancer Research, 3rd Medical Department with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncologic Center, Paracelsus Medical University, Salzburg, Austria;Salzburg Cancer Research Institute, Austria

Susanne Pucher

Laboratory for Immunological and Molecular Cancer Research, 3rd Medical Department with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncologic Center, Paracelsus Medical University, Salzburg, Austria;Salzburg Cancer Research Institute, Austria

Claudia Zelle-Rieser

Tyrolean Cancer Research Institute, Innsbruck, Austria

Karin Jöhrer

Tyrolean Cancer Research Institute, Innsbruck, Austria

Maikel Wijtmans

Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Division Medicinal Chemistry, VU University Amsterdam, the Netherlands

Rob Leurs

Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Division Medicinal Chemistry, VU University Amsterdam, the Netherlands

Martine J. Smit

Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Division Medicinal Chemistry, VU University Amsterdam, the Netherlands

Valter Gattei

Clinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico, Aviano, Italy

Richard Greil

Laboratory for Immunological and Molecular Cancer Research, 3rd Medical Department with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncologic Center, Paracelsus Medical University, Salzburg, Austria;Salzburg Cancer Research Institute, Austria

Tanja N. Hartmann

Laboratory for Immunological and Molecular Cancer Research, 3rd Medical Department with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncologic Center, Paracelsus Medical University, Salzburg, Austria;Salzburg Cancer Research Institute, Austria