Canadian Respiratory Journal (Jan 2000)

A Randomised Controlled Trial of High Dose, Inhaled Budesonide Versus Oral Prednisone in Patients Discharged from the Emergency Department following an Acute Asthma Exacerbation

  • J Mark FitzGerald,
  • David Shragge,
  • Jennifer Haddon,
  • Barbara Jennings,
  • Joanna Lee M Math,
  • Tony Bai,
  • Peter Pare,
  • David Kassen,
  • Anton Grunfeld

DOI
https://doi.org/10.1155/2000/587957
Journal volume & issue
Vol. 7, no. 1
pp. 61 – 67

Abstract

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OBJECTIVE: Prednisone (PRED) is recommended at discharge to reduce the relapse rate following emergency treatment for an asthmatic attack. However, PRED has systemic side effects. Inhaled anti-inflammatory medications, such as budesonide (BUD), are well tolerated. This study was designed to compare the effectiveness of PRED and BUD on relapse rate.