Structure and properties of microcellulose-based coatings deposited via a low-energy electron beam and their effect on the properties of onto wound dressings

Yiming Liu; Xu Qin; A.V. Rogachev; A.A. Rogachev; I.I. Kontsevaya; A.E. Pyzh; Xiaohong Jiang; V.A. Yarmolenko; A.S. Rudenkov; M.A. Yarmolenko

Carbohydrate Polymer Technologies and Applications (Dec 2021)

Structure and properties of microcellulose-based coatings deposited via a low-energy electron beam and their effect on the properties of onto wound dressings

Yiming Liu,
Xu Qin,
A.V. Rogachev,
A.A. Rogachev,
I.I. Kontsevaya,
A.E. Pyzh,
Xiaohong Jiang,
V.A. Yarmolenko,
A.S. Rudenkov,
M.A. Yarmolenko

Affiliations

Yiming Liu: International Chinese-Belorussian Scientific Laboratory on Vacuum-Plasma Technology, Nanjing University of Science and Technology, 200, Xiaolingwei Street, Nanjing 210094, China; Francisk Skorina Gomel State University, 104, Sovetskaya Street, Gomel 246019, Belarus
Xu Qin: International Chinese-Belorussian Scientific Laboratory on Vacuum-Plasma Technology, Nanjing University of Science and Technology, 200, Xiaolingwei Street, Nanjing 210094, China
A.V. Rogachev: International Chinese-Belorussian Scientific Laboratory on Vacuum-Plasma Technology, Nanjing University of Science and Technology, 200, Xiaolingwei Street, Nanjing 210094, China; Francisk Skorina Gomel State University, 104, Sovetskaya Street, Gomel 246019, Belarus
A.A. Rogachev: International Chinese-Belorussian Scientific Laboratory on Vacuum-Plasma Technology, Nanjing University of Science and Technology, 200, Xiaolingwei Street, Nanjing 210094, China; Institute of Chemistry of New Materials of the National Academy of Sciences of Belarus, 36, F. Skoriny, Minsk 220141, Belarus
I.I. Kontsevaya: Francisk Skorina Gomel State University, 104, Sovetskaya Street, Gomel 246019, Belarus
A.E. Pyzh: Institute of Physiology National Academy of Sciences of Belarus, 28, Academicheskaya Street, Minsk 220072, Belarus
Xiaohong Jiang: International Chinese-Belorussian Scientific Laboratory on Vacuum-Plasma Technology, Nanjing University of Science and Technology, 200, Xiaolingwei Street, Nanjing 210094, China; Corresponding authors.
V.A. Yarmolenko: Gomel State Medical University, 5, Lange Street, Gomel 246000, Belarus
A.S. Rudenkov: International Chinese-Belorussian Scientific Laboratory on Vacuum-Plasma Technology, Nanjing University of Science and Technology, 200, Xiaolingwei Street, Nanjing 210094, China; Francisk Skorina Gomel State University, 104, Sovetskaya Street, Gomel 246019, Belarus
M.A. Yarmolenko: International Chinese-Belorussian Scientific Laboratory on Vacuum-Plasma Technology, Nanjing University of Science and Technology, 200, Xiaolingwei Street, Nanjing 210094, China; Francisk Skorina Gomel State University, 104, Sovetskaya Street, Gomel 246019, Belarus; Corresponding authors.

Journal volume & issue: Vol. 2
p. 100146

Abstract

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The molecular structure and properties of a three-layer system based on CaH2, P2O5, microcrystalline cellulose + miramistin deposited via a low-energy electron beam onto a wound dressing have been considered. A cross-linked cellulose layer containing carbon particles and a drug component serves as the coating. The cross-linked structure of the coating enhances the resistance of the miramistin to thermal degradation. The high sorption activity of the gauze substrate determines the exponential nature of the change in the miramistin concentration in the solution. The deposition of a three-layer coating (CaH2 + P2O5 + (cellulose + miramistin)) allows imparting prolonged antibacterial (E. coli, S. aureus) and antifungal (C. alibicans) properties to gauze dressings, reducing the rate of moisture desorption from its volume as a result of the hydrogel formation on the surface of the fibers. Here, the hydrogel formation affects the decrease (over two times) in the gauze's ability to sorb moisture.

Published in Carbohydrate Polymer Technologies and Applications

ISSN: 2666-8939 (Online)
Publisher: Elsevier
Country of publisher: United Kingdom
LCC subjects: Science: Chemistry: Organic chemistry: Biochemistry
Website: https://www.journals.elsevier.com/carbohydrate-polymer-technologies-and-applications

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