Radiology and Oncology (Feb 2016)

Electrochemotherapy in pancreatic adenocarcinoma treatment: pre-clinical and clinical studies

  • Bimonte Sabrina,
  • Leongito Maddalena,
  • Granata Vincenza,
  • Barbieri Antonio,
  • Vecchio Vitale del,
  • Falco Michela,
  • Nasto Aurelio,
  • Albino Vittorio,
  • Piccirillo Mauro,
  • Palaia Raffaele,
  • Amore Alfonso,
  • Giacomo Raimondo di,
  • Lastoria Secondo,
  • Setola Sergio Venanzio,
  • Fusco Roberta,
  • Petrillo Antonella,
  • Izzo Francesco

DOI
https://doi.org/10.1515/raon-2016-0003
Journal volume & issue
Vol. 50, no. 1
pp. 14 – 20

Abstract

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Pancreatic adenocarcinoma is currently one of the deadliest cancers with high mortality rate. This disease leads to an aggressive local invasion and early metastases, and is poorly responsive to treatment with chemotherapy or chemo-radiotherapy. Radical resection is still the only curative treatment for pancreatic cancer, but it is generally accepted that a multimodality strategy is necessary for its management. Therefore, new alternative therapies have been considered for local treatment.

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