Seroprevalence of Hepatitis B &C and its Association with Stroke in Local Population

Abstract

Background: Pandemics of viral origin are spreading at alarming rate worldwide. Acquired immune deficiency syndrome (AIDS) caused by human immunodeficiency virus (HIV), hepatitis B and Hepatitis C (HCV) are lethal threats to the human health. HCV remains a serious issue due to long-term consequences of the infection. HCV infection has a role in the development and progression of carotid atherosclerosis and stroke due to altered lipid metabolism. Association of hepatitis with stroke is still hypothesized due to conflicting results documented by various researchers. Aim of this study is to explore association of HBV and HCV with stroke as the prevalence of this issue in Faisalabad is 21% which is higher than other regions of Punjab Pakistan. Methods: This is a hospital-based retrospective study from July 2018 to September 2018 at a private hospital of Faisalabad. It comprised of 226 subjects. After taking ethical approval from the ethic research committee, data was retrieved from centrally database medical records. Data was transported to SPSS 21 for analysis. Frequency and percentages were obtained for categorical variables. Association between hepatitis and stroke was tested by Chi square and logistic regression to obtained odd ratio. P value?0.05 was considered as significant. Results: Mean age of the studied population was 51.2 ± 27.03. 38.5% and 4% of the studied population had hepatitis C and B respectively. HCV was significantly associated with stroke (P=.005*) Conclusion: HCV is more prevalent viral infection in local population and is the independent risk factor for stroke

Keywords

• HBV ,HCV, Stroke, Association, lipid metabolism