Nature Communications (Dec 2018)

Escherichia coli can survive stress by noisy growth modulation

  • Om Patange,
  • Christian Schwall,
  • Matt Jones,
  • Casandra Villava,
  • Douglas A. Griffith,
  • Andrew Phillips,
  • James C. W. Locke

DOI
https://doi.org/10.1038/s41467-018-07702-z
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 11

Abstract

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Noisy gene expression leading to phenotypic variability can help organisms to survive in changing environments. Here, Patange et al. show that noisy expression of a stress response regulator, RpoS, allows E. coli cells to modulate their growth rates to survive future adverse environments.