Nature Communications (Jan 2016)
Systematic identification of genes with a cancer-testis expression pattern in 19 cancer types
- Cheng Wang,
- Yayun Gu,
- Kai Zhang,
- Kaipeng Xie,
- Meng Zhu,
- Ningbin Dai,
- Yue Jiang,
- Xuejiang Guo,
- Mingxi Liu,
- Juncheng Dai,
- Linxiang Wu,
- Guangfu Jin,
- Hongxia Ma,
- Tao Jiang,
- Rong Yin,
- Yankai Xia,
- Li Liu,
- Shouyu Wang,
- Bin Shen,
- Ran Huo,
- Qianghu Wang,
- Lin Xu,
- Liuqing Yang,
- Xingxu Huang,
- Hongbing Shen,
- Jiahao Sha,
- Zhibin Hu
Affiliations
- Cheng Wang
- State Key Laboratory of Reproductive Medicine, Nanjing Medical University
- Yayun Gu
- State Key Laboratory of Reproductive Medicine, Nanjing Medical University
- Kai Zhang
- State Key Laboratory of Reproductive Medicine, Nanjing Medical University
- Kaipeng Xie
- State Key Laboratory of Reproductive Medicine, Nanjing Medical University
- Meng Zhu
- State Key Laboratory of Reproductive Medicine, Nanjing Medical University
- Ningbin Dai
- State Key Laboratory of Reproductive Medicine, Nanjing Medical University
- Yue Jiang
- State Key Laboratory of Reproductive Medicine, Nanjing Medical University
- Xuejiang Guo
- State Key Laboratory of Reproductive Medicine, Nanjing Medical University
- Mingxi Liu
- State Key Laboratory of Reproductive Medicine, Nanjing Medical University
- Juncheng Dai
- State Key Laboratory of Reproductive Medicine, Nanjing Medical University
- Linxiang Wu
- Department of Bioinformatics, School of Basic Medical Sciences, Nanjing Medical University
- Guangfu Jin
- State Key Laboratory of Reproductive Medicine, Nanjing Medical University
- Hongxia Ma
- State Key Laboratory of Reproductive Medicine, Nanjing Medical University
- Tao Jiang
- State Key Laboratory of Reproductive Medicine, Nanjing Medical University
- Rong Yin
- Jiangsu Key Laboratory of Molecular and Translational Cancer Research, Collaborative Innovation Center For Cancer Personalized Medicine, Nanjing Medical University Affiliated Cancer Hospital
- Yankai Xia
- Department of Molecular Cell Biology and Toxicology, Jiangsu Key Lab of Cancer Biomarkers, Prevention & Treatment, Collaborative Innovation Center For Cancer Personalized Medicine, School of Public Health, Nanjing Medical University
- Li Liu
- Digestive Endoscopy Center, the First Affiliated Hospital of Nanjing Medical University
- Shouyu Wang
- Department of Molecular Cell Biology and Toxicology, Jiangsu Key Lab of Cancer Biomarkers, Prevention & Treatment, Collaborative Innovation Center For Cancer Personalized Medicine, School of Public Health, Nanjing Medical University
- Bin Shen
- State Key Laboratory of Reproductive Medicine, Nanjing Medical University
- Ran Huo
- State Key Laboratory of Reproductive Medicine, Nanjing Medical University
- Qianghu Wang
- Department of Bioinformatics, School of Basic Medical Sciences, Nanjing Medical University
- Lin Xu
- Jiangsu Key Laboratory of Molecular and Translational Cancer Research, Collaborative Innovation Center For Cancer Personalized Medicine, Nanjing Medical University Affiliated Cancer Hospital
- Liuqing Yang
- Department of Molecular and Cellular Oncology, Cancer Biology Program, Center for RNA Interference and Non-Coding RNAs, the University of Texas MD Anderson Cancer Center
- Xingxu Huang
- School of Life Science and Technology, Shanghai Tech University
- Hongbing Shen
- State Key Laboratory of Reproductive Medicine, Nanjing Medical University
- Jiahao Sha
- State Key Laboratory of Reproductive Medicine, Nanjing Medical University
- Zhibin Hu
- State Key Laboratory of Reproductive Medicine, Nanjing Medical University
- DOI
- https://doi.org/10.1038/ncomms10499
- Journal volume & issue
-
Vol. 7,
no. 1
pp. 1 – 12
Abstract
Genes normally expressed in the testis but aberrantly expressed in cancer are termed cancer testis antigens. In this study, the authors catalogue the expression of these genes in 19 different cancer types and correlate expression with some somatically mutated oncogenes.
