Successful Treatment of Poikilodermatous Mycosis Fungoides with 308-nm Excimer Laser

Abstract

Introduction: Among the spectrum of mycosis fungoides (MF), poikilodermatous MF (PMF) is a rare clinical variant of patch-stage MF, which is characterized by cutaneous atrophy, mottled-reticular pigmentation, and telangiectasia. Given its favorable prognosis, ultraviolet (UV) light therapy, such as narrowband UVB (NB-UVB), is commonly employed for the treatment of PMF. Notably, the 308-nm excimer laser emits high-energy monochromatic light with a wavelength close to the NB-UVB peak. Case Presentation: Herein, we report a case of PMF successfully treated with the 308-nm excimer laser. Conclusion: There have been no English-language case reports describing the use of excimer laser treatment for PMF, and this is the first English report that suggests the usefulness of the 308-nm excimer laser for the treatment of PMF, which is one of the clinical variants of patch-stage of MF.