Optical coherence tomography findings of bilateral foveal leukemic infiltration

Abstract

John Q Le,1 Puneet S Braich,2 Vikram S Brar2 1Department of Internal Medicine, 2Department of Ophthalmology, Virginia Commonwealth University, Richmond, VA, USA Abstract: We report a case of a 59-year-old man with a history of atypical chronic myelogenous leukemia who presented with a several-week history of decreased vision in both eyes. His clinical examination revealed bilateral foveal infiltration, which was also demonstrated on optical coherence tomography. After a failed induction with imatinib (Gleevec®), he was treated with omacetaxine (Synribo®) with an appropriate hematologic response. As his leukemia improved with chemotherapy, his retinal lesions regressed as demonstrated by serial optical coherence tomography and fundus photographs, with near complete restoration of foveal architecture. Keywords: leukemia, leukemic retinopathy, leukemic infiltration, OCT

Keywords

• Leukemia
• Leukemic Retinopathy
• Leukemic Infiltration
• OCT