Bioengineering (Sep 2021)

Success of Thrombectomy in Management of Ischemic Stroke in Two Patients with SynCardia Total Artificial Heart in Bridge-to-Transplantation

  • Brendan Le Picault,
  • Charles-Henri David,
  • Pierre-Louis Alexandre,
  • Cédric Lenoble,
  • Philippe Bizouarn,
  • Thierry Lepoivre,
  • Nicolas Groleau,
  • Bertrand Rozec,
  • Hubert Desal,
  • Jean-Christian Roussel,
  • Thomas Sénage

DOI
https://doi.org/10.3390/bioengineering8090126
Journal volume & issue
Vol. 8, no. 9
p. 126

Abstract

Read online

Introduction: Circulatory assistance from a SynCardia Total Artificial Heart (SynCardia-TAH) is a reliable bridge-to-transplant solution for patients with end-stage biventricular heart failure. Ischemic strokes affect about 10% of patients with a SynCardia-TAH. We report for the first time in the literature two successful thrombectomies to treat the acute phase of ischemic stroke in two patients treated with a SynCardia-TAH in the bridge-to-transplant (BTT). Case report: We follow two patients with circulatory support from a SynCardia-TAH in the bridge-to-transplant for terminal biventricular cardiac failure with ischemic stroke during the support period. An early in-hospital diagnosis enables the completion of a mechanical thrombectomy within the first 6 h of the onset of symptoms. There was no intracranial hemorrhagic complication during or after the procedure and the patients fully recovered from neurological deficits, allowing a successful heart transplant. Conclusion: This case report describes the possibility of treating ischemic strokes under a SynCardia-TAH by mechanical thrombectomy following the same recommendations as for the general population with excellent results and without any hemorrhagic complication during or after the procedure.

Keywords