Remodeling of gene regulatory networks underlying thermogenic stimuli-induced adipose beiging

Seoyeon Lee; Abigail M. Benvie; Hui Gyu Park; Roman Spektor; Blaine Harlan; J. Thomas Brenna; Daniel C. Berry; Paul D. Soloway

doi:10.1038/s42003-022-03531-5

Communications Biology (Jun 2022)

Remodeling of gene regulatory networks underlying thermogenic stimuli-induced adipose beiging

Seoyeon Lee,
Abigail M. Benvie,
Hui Gyu Park,
Roman Spektor,
Blaine Harlan,
J. Thomas Brenna,
Daniel C. Berry,
Paul D. Soloway

Affiliations

Seoyeon Lee: Division of Nutritional Sciences, College of Agriculture and Life Sciences, Cornell University, Ithaca
Abigail M. Benvie: Division of Nutritional Sciences, College of Agriculture and Life Sciences, Cornell University, Ithaca
Hui Gyu Park: Dell Pediatric Research Institute, Departments of Chemistry, Pediatrics, and Nutrition, Dell Medical School and the College of Natural Sciences, University of Texas at Austin
Roman Spektor: Field of Genetics, Genomics, and Development, Department of Molecular Biology and Genetics, Cornell University, Ithaca
Blaine Harlan: Field of Genetics, Genomics, and Development, Department of Molecular Biology and Genetics, Cornell University, Ithaca
J. Thomas Brenna: Division of Nutritional Sciences, College of Agriculture and Life Sciences, Cornell University, Ithaca
Daniel C. Berry: Division of Nutritional Sciences, College of Agriculture and Life Sciences, Cornell University, Ithaca
Paul D. Soloway: Division of Nutritional Sciences, College of Agriculture and Life Sciences, Cornell University, Ithaca

DOI: https://doi.org/10.1038/s42003-022-03531-5
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 16

Abstract

Read online

Adipocyte beiging is a thermogenic response to cold exposure and b3-adrenergic receptor agonists, which exert their effects by distinct and common molecular mechanisms that control chromatin accessibility and lipid metabolism.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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