European Journal of Medical Research (Dec 2009)

Total and antigen-specific Ige levels in umbilical cord blood

  • Sybilski AJ,
  • Doboszynska A,
  • Samolinski B

DOI
https://doi.org/10.1186/2047-783X-14-S4-233
Journal volume & issue
Vol. 14, no. Suppl 4
pp. 233 – 236

Abstract

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Abstract The present study was conducted to learn whether the perinatal and environmental factors could influence the total and antigen-specific IgE levels in umbilical cord blood. Retrospective data were obtained from 173 mother-infant pairs. Total and specific (for children's food, wheat/grass and house dust mite-HDM) cord blood IgE levels were determined using the immunoassay test. The total cord blood IgE was between 0.0-23.08 IU/ml (mean 0.55 ± 2.07 IU/ml; median 0.16 IU/ml). Total IgE levels were significantly higher in boys compared with girls (OR = 2.2; P = 0.007), and in newborns with complicated pregnancy (OR = 2.7; P = 0.003). A greater number of siblings correlated with increases in the total cord blood IgE (P

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