Diagnostic accuracy of computed tomography in Wilm's tumour taking histopathology as gold standard in symptomatic renal masses at a tertiary care hospital, Karachi.

Abstract

Background:Recent advances in imaging technology has made it possible to diagnose abdominal masses in the early stages along with accurate image-guided localization of biopsy sites. Contrast-enhanced Computed tomography (CECT) abdomen is one such imaging tool. This study aims to establish the diagnostic accuracy of CT scans in detecting Wilm's tumour.Methodology:This descriptive cross-sectional study was conducted in the Department of Radiology, Sindh Institute of Urology and Transplantation (SIUT), Karachi, from 20-10-2018 till 04-20-2019. A total of 196 patients who were clinically suspected of renal masseswere included in this research project. CECT scan abdomen was acquired. The final diagnosis was based on histopathology.Results:Mean age in our study was 13.4±5.7 months. 104 (53.1%) were male, and 92 (46.9%) were female, respectively. Moreover, out of 196 patients, sensitivity, specificity, both the positive and negative predictive value along with diagnostic accuracy of CECT scan for diagnosis of Wilm's tumour by taking histopathology as the gold standard was found to be 93.4%, 91.8%, 95%, 89.4% and 92.8% respectively.Conclusion:It is concluded from the study results that the AbdominalCECT scan, despite its high radiation dose, is relevant and accurate in making a diagnosis of Wilms tumour, making it significantly helpful in early disease detection in poor resource settings such as ours where patients usually present late for treatment.

Keywords

• wilm’s tumour
• cect scan
• histopathology
• symptomatic renal mass