Prospects for the use of selective estrogen receptor modulator tamoxifen

Abstract

The review presents a contemporary data concerning the use of tamoxifen in wide range of pathological conditions: central nervous system diseases and mechanisms of neuroprotective action of estrogen receptors, pituitary tumors with the accent on the treatment of prolactinomas, infertility treatment. We also discuss the risks of tamoxifen treatment for pregnancy induction in women including complications of pregnancy, fetus malformations.

Keywords

• tamoxifen
• pregnancy
• nervous system
• pituitary adenoma
• anovulation