PLoS ONE (Jan 2021)

Burden of Hypertensive Heart Disease in Iran during 1990-2017: Findings from the Global Burden of Disease study 2017.

  • Negar Omidi,
  • Jalal Arabloo,
  • Aziz Rezapour,
  • Farshid Alaeddini,
  • Nicola Luigi Bragazzi,
  • Hamid Pourasghari,
  • Masoud Behzadifar,
  • Mojtaba Salarifar,
  • MohammdRafie Khorgami,
  • Seyyed Mojtaba Ghorashi,
  • Samad Azari

DOI
https://doi.org/10.1371/journal.pone.0257617
Journal volume & issue
Vol. 16, no. 9
p. e0257617

Abstract

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BackgroundHypertension and its consequent end-organ damage including Hypertensive Heart Disease (HHD) are a major concern that impact health, resulting into impairment and reduced quality of life (QOL). The purpose of this study was to describe the burden of HHD in Iran and comparing it with the World Bank upper middle-income countries (UMICs) in terms of disability-adjusted life years (DALY), mortality and prevalence.MethodsUsing data from the Global Burden of Disease study 2017, we compared the number of DALYs, deaths and prevalence trends for HHD from 1990 to 2017 in all age groups for both sex in Iran, and compared the epidemiology and trends with UMICs and globally.ResultsThe age-standardized DALY rate for HHD increased by 51.6% for men (95% uncertainty interval [UI] 305.8 to 436.7 per 100,000) and 4.4% for women (95% UI 429.4 to 448.7 per 100,000) in Iran. The age-standardized prevalence of HHD in Iran was almost twice times higher than globally and 1.5-times more than the World Bank UMICs. The age-standardized death rate for HDD increased by 60.1% (95% UI 17.3 to 27.7% per 100,000) for men and by 21.7% (95% UI 25.85 to 31.48 per 100,000) for women from 1990 to 2017. Age-standardized death rate in Iran was 2.4 and 1.9 times higher than globally and UMICs, respectively.ConclusionsThe higher prevalence and death rate in Iran in comparison with UMICs and globally should encourage health care provider to perform intensive screening activities in at risk population to prevent HHD and mitigate its mortality.