THE CLINIC-ANAMNESTIC FEATURES OF PSORIASIS AT ADULT PERSONS IN BAKU

Abstract

Background. Currently, psoriasis is one of the most common chronic dermatoses, which affects 1 to 3% of the world's population. Purpose. The purpose of this study is to study the epidemiological features of the spread of psoriasis and to give a microbiological characteristic of the causative agents of psoriasis among men in Baku. Material and methods of study. In the context of the purpose and objectives of the study, 490 men admitted to the Republican Dermatovenerologic Dispensary in 2018-2019. were examined for Psoriasis (in 2018 - 225 people (45.9%), in 2019 - 265 people (54.1%)). The mean age of the patients was 22.3±3.6 years. The age structure of the surveyed men was as follows: up to 18 years old - 33 people. (6.7%); 18-29 years old - 442 men (90.2%); over 30 years old - 15 people. (3.1%). All patients were examined by traditional research methods (history taking, general bacterioscopy, mycological studies, etc.). If necessary, an endocrinologist, gynecologist and allergist were consulted. During statistical processing of the obtained results of the study, the mean value (M), the standard error of the mean value (m), and the extensive incidence rate (%) in different age groups were determined. The difference between the results was considered statistically significant at p<0.05. Results. Among all examined men (490 people), mono pathology was found in 439 patients (89.6%), mixed pathology - in 34 (6.9%). The diagnosis of "Psoriasis" was established in 214 men, which is 43.7±2.2%. The results of mycological studies showed the presence of fungi in 233 patients with an established diagnosis (47.6%). With established monopathologies, various pathogens were found in 232 patients (47.3%), mixed pathologies - in 4 (0.8%). Among the isolated bacterial pathogens, St.aureus was identified in 4 cases (0.8%), St.epidermidis - in 3 cases (0.6%). Among pathogen associates, the frequency of occurrence of associations of fungi of the genus Candida + St.aureus and fungi of the genus Candida + St.epidermidis was 0.4±0.3%, respectively. An analysis of the detection of psoriasis in men depending on age showed that up to 18 years of age in patients psoriasis was determined in 48.5 ± 8.7 (16 people), in the age group of 18-29 years in 43.9 ± 2.4 % (194 men) and in the age group over 30 years old - in 26.7±11.4% (4 cases). When studying the detectability of mono and mixed pathologies depending on age groups, it was found that both mono and mixed pathologies were more recorded in the age group of 18-29 years - 91.1±1.4% and 79.4±6.9%, respectively. (χ2=59.255; df=22; s=0.000). Various bacterial pathogens and fungi of the genus Candida were found in monopathologies in 47.6±2.4%, in mixed pathologies in 0.9±0.5%. Conclusions. Based on the results obtained by us, it was established that the age group of 18-29 years old (43.9±9.2%) was the risk group by age. Risk factors for pathogens were mainly fungi of the genus Candida and bacterial pathogens, in particular St.aureus and St.epidermidis. Seasonal risk factor can be distinguished by the spring-summer seasonality of psoriasis. It was found that the detection rate of psoriasis is 43.7±2.2%. Mono-pathology was detected in 89.9±1.4% of cases, mixed pathology - in 6.9±1.1%. The highest detection rate of psoriasis was observed in the age group of 18-29 years - 43.9±2.4%. Among the associates of pathogens, the frequency of occurrence of associations of fungi of the genus Candida + St.epidermidis was 0.4±0.3%, respectively. It is shown that psoriasis was more detected in the spring months, but in general, showed a spring-summer seasonality.

Keywords

• psoriasis
• men
• prevalence
• risk group
• risk factor
• seasonality
• baku