Antibacterial activity of Vitex parviflra A.Juss. and Cyanthillium cinereum (L.) H.Rob. against human pathogens

Asian Pacific Journal of Tropical Disease. 2016;6(12):1004-1006 DOI 10.1016/S2222-1808(16)61173-8

 

Journal Homepage

Journal Title: Asian Pacific Journal of Tropical Disease

ISSN: 2222-1808 (Print)

Publisher: Asian Pacific Journal of Tropical Disease Editorial Office

Society/Institution: Hainan Medical University

LCC Subject Category: Medicine: Internal medicine: Special situations and conditions: Arctic medicine. Tropical medicine

Country of publisher: China

Language of fulltext: English

Full-text formats available: PDF, HTML

 

AUTHORS

Ourlad Alzeus G. Tantengco (College of Medicine, University of the Philippines Manila, Pedro Gil Street, Ermita, Manila, Philippines)
Marlon Lian C. Condes (Department of Biology, College of Arts and Sciences, University of the Philippines Manila, Padre Faura Steet, Ermita, Manila, Philippines)
Hanna Hasmin T. Estadilla (Department of Biology, College of Arts and Sciences, University of the Philippines Manila, Padre Faura Steet, Ermita, Manila, Philippines)
Elena M. Ragragio (Department of Biology, College of Arts and Sciences, University of the Philippines Manila, Padre Faura Steet, Ermita, Manila, Philippines)

EDITORIAL INFORMATION

Peer review

Editorial Board

Instructions for authors

Time From Submission to Publication: 6 weeks

 

Abstract | Full Text

This study investigated the antibacterial activities of methanolic crude extracts of Vitex parviflora (V. parviflora) leaves and stem and Cyanthillium cinereum (C. cinereum) leaves and roots. Crude methanolic extracts of V. parviflora and C. cinereum were tested for their antibacterial activities against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Bacillus subtilis. The leaf and stem extracts of V. parviflora and root extracts of C. cinereum exhibited high antibacterial activity against Staphylococcus aureus. Increasing concentration of the V. parviflora leaves and roots crude extracts resulted in an increasing antistaphylococcal activity as exhibited by increasing diameters of zone of inhibition. Root extracts of C. cinereum exhibited inverse dose-response relationship. The anti-staphylococcal activity was the highest at the lowest concentration (25 mg/mL) and it decreased as the concentration increased. This study established the anti-staphylococcal activity of methanolic crude extracts of V. parviflora leaves and stem and C. cinereum roots. This study also validated the use of these plants in folkloric medicines in the indigenous communities in the Philippines.