Clozapine Induced Neuroleptic Malignant Syndrome

Abstract

Neuroleptic malignant syndrome is a rare, but potentially life-threatening adverse event associated with the use of neuroleptic agents. We describe the case of a 47-year-old schizophrenic woman who was treated with clozapine for years. The patient developed acute renal failure with pulmonary edema, and underwent mechanical ventilation and hemodialysis.

Keywords

• clozapine
• neuroleptic malignant syndrome
• rhabdomyolysis
• acute kidney injury