Redox Biology (Jun 2021)

Ergothioneine, recent developments

  • Irwin K. Cheah,
  • Barry Halliwell

Journal volume & issue
Vol. 42
p. 101868


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There has been a recent surge of interest in the unique low molecular weight dietary thiol/thione, ergothioneine. This compound can accumulate at high levels in the body from diet and may play important physiological roles in human health and development, and possibly in prevention and treatment of disease. Blood levels of ergothioneine decline with age and onset of various diseases. Here we highlight recent advances in our knowledge of ergothioneine.