Odontogenic Carcinosarcoma of the Mandible, a Case Report

Abstract

Odontogenic carcinosarcoma is an extremely rare malignant mixed odontogenic tumor, in which both epithelial and mesenchymal component showing malignant cytology features. Due to paucity of reported cases, clinical appearance is unclear. Present study reports a mandibular odontogenic carcinosarcoma in a 33 years-old male with a history of painless mass in the anterior of mandible. The histopathological examination demonstrated a biphasic malignant neoplasm with both epithelial and mesenchymal component malignant features. There were follicles and strands of odontogenic epithelium, which were lined peripherally by ameloblast-like cells. Mesenchyme of tumor was highly cellular resembling dental papilla. Partial mandibular resection, consisting wide surgical excision with immediate reconstruction was accomplished.

Keywords

• odontogenic carcinosarcoma; ameloblastic carcinosarcoma; malignant mixed odontogenic tumor; mandible