Noncanonical necrosis in 2 different cell types in a Caenorhabditis elegans NAD+ salvage pathway mutant

Rifath N Reza; Nicholas D Serra; Ariana C Detwiler; Wendy Hanna-Rose; Matt Crook

doi:10.1093/g3journal/jkac033

G3: Genes, Genomes, Genetics (Feb 2022)

Noncanonical necrosis in 2 different cell types in a Caenorhabditis elegans NAD+ salvage pathway mutant

Rifath N Reza,
Nicholas D Serra,
Ariana C Detwiler,
Wendy Hanna-Rose,
Matt Crook

Affiliations

Rifath N Reza: Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA 16802, USA
Nicholas D Serra: Department of Genetics, University of Pennsylvania, Philadelphia, PA 19104, USA
Ariana C Detwiler: ORCiD; Department of Environmental and Occupational Health, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15261, USA
Wendy Hanna-Rose: ORCiD; Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA 16802, USA
Matt Crook: ORCiD; Department of Life Sciences, Texas A&M University-San Antonio, San Antonio, TX 78224, USA

DOI: https://doi.org/10.1093/g3journal/jkac033
Journal volume & issue: Vol. 12, no. 4

Abstract

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AbstractNecrosis was once described as a chaotic unregulated response to cellular insult. We now know that necrosis is controlled by multiple pathways in response to many different cellular conditions. In our pnc-1+Caenorhabditis eleganspnc-1C. elegansmec-4dced-4pnc-1

Published in G3: Genes, Genomes, Genetics

ISSN: 2160-1836 (Online)
Publisher: Oxford University Press
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General): Genetics
Website: https://academic.oup.com/g3journal

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