Emodin Suppresses Proliferation, Migration and Invasion in Ovarian Cancer Cells by down Regulating ILK in vitro and in vivo [Retraction]

Abstract

Lu JJ, Xu Y, Zhao Z, et al. Onco Targets Ther. 2017;10:3579–3589. At the authors request, the Editor and Publisher of OncoTargets and Therapy wish to retract the published article. The authors raised concerns after discovering the duplication of cell migration and invasion images in Figures 1 and 2. Specifically, Figure 1E, A2780, Migration, Normal appears to have been duplicated with Figure 1E, A2780, Migration pLVX-Con. Figure 1E, SK-OV-3, Invasion, Normal appears to have been duplicated with Figure 2C, SK-OV-3, Invasion, pLVX-Con+, pLVX-ILK-, Emodin-. The authors provided original data and requested to retract the article. All the authors agreed that the retraction was necessary for reasons of scientific accuracy. The Editor agreed with this decision. Our decision-making was informed by our policy on publishing ethics and integrity and the COPE guidelines on retraction. The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as “Retracted”.

Keywords

• emodin
• ilk
• epithelial ovarian cancer
• epithelial-mesenchymal transition
• slug
• xenografts in nude mice