Response to: 500 mg as bolus followed by an extended infusion of 1500 mg of meropenem every 8 h failed to achieve in one-third of the patients an optimal PK/PD against nonresistant strains of these organisms: is CRRT responsible for this situation?

• Amol Kothekar,
• Jigeeshu Vasishtha Divatia,
• Sheila Nainan Myatra,
• Vikram Gota

Affiliations

Amol Kothekar

Department of Anesthesiology, Critical Care and Pain, Tata Memorial Centre, Homi Bhabha National Institute

Jigeeshu Vasishtha Divatia

Department of Anesthesiology, Critical Care and Pain, Tata Memorial Centre, Homi Bhabha National Institute

Sheila Nainan Myatra

Department of Anesthesiology, Critical Care and Pain, Tata Memorial Centre, Homi Bhabha National Institute

Vikram Gota

Department of Clinical Pharmacology, ACTREC, Tata Memorial Centre, Homi Bhabha National Institute