Nature Communications (Jun 2022)

Pre-existing antibody levels negatively correlate with antibody titers after a single dose of BBV152 vaccination

  • Suman Das,
  • Janmejay Singh,
  • Heena Shaman,
  • Balwant Singh,
  • Anbalagan Anantharaj,
  • Patil Sharanabasava,
  • Rajesh Pandey,
  • Rakesh Lodha,
  • Anil Kumar Pandey,
  • Guruprasad R. Medigeshi

DOI
https://doi.org/10.1038/s41467-022-31170-1
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 7

Abstract

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Serosurveillance studies show a heterogenous mix of the Indian population with immunity to COVID-19 due to vaccination or natural infection. Here, the authors enrol subjects representative of the general population, to assess whether pre-existing antibodies are further boosted by a single dose of an inactivated SARS-CoV-2 vaccines, BBV152.