Nature Communications (Mar 2017)

In vivo gastrointestinal drug-release monitoring through second near-infrared window fluorescent bioimaging with orally delivered microcarriers

  • Rui Wang,
  • Lei Zhou,
  • Wenxing Wang,
  • Xiaomin Li,
  • Fan Zhang

DOI
https://doi.org/10.1038/ncomms14702
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 12

Abstract

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The sustained release of drugs within the gastrointestinal tract as well as their detection following administration is a challenge. Here, the authors develop a microcarrier that supported sustained drug release in the gastrointestinal tractin vivoand could be monitored with real-time imaging.