BMC Biology (May 2010)

Hidden reach of the micromanagers

  • Jackson Aimee L,
  • Linsley Peter S

DOI
https://doi.org/10.1186/1741-7007-8-53
Journal volume & issue
Vol. 8, no. 1
p. 53

Abstract

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Abstract Small interfering RNAs can trigger unintended, microRNA-like off-target effects, but the impact of these effects on functional studies has been controversial. A recent study in BMC Genomics shows that microRNA-like effects can predominate among the 'hits' of functional genomics screens. See research article http://www.biomedcentral.com/1471-2164/11/175